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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15
All Species:
18.18
Human Site:
T442
Identified Species:
40
UniProt:
P42566
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42566
NP_001153441.1
896
98656
T442
S
Q
E
S
Q
I
S
T
Y
E
E
E
L
A
K
Chimpanzee
Pan troglodytes
XP_001139393
896
98643
T442
S
Q
E
S
Q
I
S
T
Y
E
E
E
L
A
K
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
D570
K
L
R
D
M
L
S
D
V
R
Q
K
C
Q
D
Dog
Lupus familis
XP_532580
889
97932
T429
S
Q
E
S
Q
I
S
T
Y
E
E
E
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P42567
897
98453
S442
S
Q
E
S
Q
I
S
S
Y
E
E
E
L
L
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026454
920
100691
M464
E
E
A
H
L
I
A
M
L
K
A
E
I
A
S
Frog
Xenopus laevis
O42287
1270
143652
T475
V
L
K
A
K
K
K
T
L
E
F
E
L
E
A
Zebra Danio
Brachydanio rerio
XP_002663145
1039
114340
D475
E
Q
E
Q
R
I
S
D
Y
E
E
E
L
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122937
1043
116535
T481
E
Q
E
S
V
L
R
T
Q
E
E
E
L
N
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
A591
S
Q
Q
S
N
V
K
A
Q
E
E
E
L
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34216
1381
150765
E713
E
S
Q
T
K
N
A
E
L
K
E
Q
I
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
43.2
91.5
N.A.
89.3
N.A.
N.A.
N.A.
74.6
21
50.5
N.A.
N.A.
30.1
N.A.
29.6
Protein Similarity:
100
99.7
59.5
94.5
N.A.
93.4
N.A.
N.A.
N.A.
84.1
34.9
64.4
N.A.
N.A.
48.2
N.A.
44.3
P-Site Identity:
100
100
6.6
100
N.A.
86.6
N.A.
N.A.
N.A.
20
26.6
60
N.A.
N.A.
53.3
N.A.
46.6
P-Site Similarity:
100
100
26.6
100
N.A.
93.3
N.A.
N.A.
N.A.
46.6
46.6
73.3
N.A.
N.A.
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
19
10
0
0
10
0
0
37
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
10
0
0
0
19
0
0
0
0
0
0
10
% D
% Glu:
37
10
55
0
0
0
0
10
0
73
73
82
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
55
0
0
0
0
0
0
19
0
0
% I
% Lys:
10
0
10
0
19
10
19
0
0
19
0
10
0
10
37
% K
% Leu:
0
19
0
0
10
19
0
0
28
0
0
0
73
10
0
% L
% Met:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
64
19
10
37
0
0
0
19
0
10
10
0
10
0
% Q
% Arg:
0
0
10
0
10
0
10
0
0
10
0
0
0
0
10
% R
% Ser:
46
10
0
55
0
0
55
10
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
10
0
0
0
46
0
0
0
0
0
19
10
% T
% Val:
10
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
46
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _